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ARXIV:2603.28387 · CLINICAL VLM EVALUATION · SUBMITTED 31 MAR · 20:22 UTC · FRESHNESS STALE
ARXIV:2603.28387CLINICAL VLM EVALUATIONSUBMITTED 31 MAR · 20:22 UTCFRESHNESS STALEDoan Nam Long Vu · Simone Balloccu · arXiv
This research reveals a critical 'scaffold effect' in clinical vision-language models, where prompt framing, not actual data integration, drives apparent performance gains, highlighting a significant risk for clinical deployment.
Opportunity summary
Pain This research reveals a critical 'scaffold effect' in clinical vision-language models, where prompt framing, not actual data integration, drives apparent performance gains, highlighting a significant risk for clinical deployment.
Evidence 37 refs | 3 sources | 50% coverage
Blocker Evidence unverified
This research reveals a critical 'scaffold effect' in clinical vision-language models, where prompt framing, not actual data integration, drives apparent performance gains, highlighting a significant risk for clinical deployment. We evaluate 12 open-weight vision-language…
Trustworthy clinical AI requires that performance gains reflect genuine evidence integration rather than surface-level artifacts. We evaluate 12 open-weight vision-language models (VLMs) on binary classification across two clinical neuroimaging cohorts, \textsc{FOR2107} (affective disorders) and…
ScienceToStartup currently rates this 4.0/10 on the public viability pass. Our findings demonstrate that surface evaluations are inadequate indicators of multimodal reasoning, with direct implications for the deployment of VLMs in clinical settings. Code…
Clinical VLM Evaluation moved forward this cycle; last verified April 2026. Public score 4.0/10. Production flags indicate code availability.
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This research reveals a critical 'scaffold effect' in clinical vision-language models, where prompt framing, not actual data integration, drives apparent performance gains, highlighting a significant risk for clinical deployment.
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10.48550/arXiv.2603.28387This research reveals a critical 'scaffold effect' in clinical vision-language models, where prompt framing, not actual data integration, drives apparent performance gains, highlighting a significant risk for clinical deployment.
Abstract
Trustworthy clinical AI requires that performance gains reflect genuine evidence integration rather than surface-level artifacts. We evaluate 12 open-weight vision-language models (VLMs) on binary classification across two clinical neuroimaging cohorts, \textsc{FOR2107} (affective disorders) and \textsc{OASIS-3} (cognitive decline). Both datasets come with structural MRI data that carries no reliable individual-level diagnostic signal. Under these conditions, smaller VLMs exhibit gains of up to 58\% F1 upon introduction of neuroimaging context, with distilled models becoming competitive with counterparts an order of magnitude larger. A contrastive confidence analysis reveals that merely \emph{mentioning} MRI availability in the task prompt accounts for 70-80\% of this shift, independent of whether imaging data is present, a domain-specific instance of modality collapse we term the \emph{scaffold effect}. Expert evaluation reveals fabrication of neuroimaging-grounded justifications across all conditions, and preference alignment, while eliminating MRI-referencing behavior, collapses both conditions toward random baseline. Our findings demonstrate that surface evaluations are inadequate indicators of multimodal reasoning, with direct implications for the deployment of VLMs in clinical settings.
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Proof status
unverified37 refs; 3 sources; 50% coverage.
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PROBLEM
This research reveals a critical 'scaffold effect' in clinical vision-language models, where prompt framing, not actual data integration, drives apparent performance gains, highlighting a significant risk for clinical deployment. We evaluate 12 open-weight vision-language models...
METHOD
Trustworthy clinical AI requires that performance gains reflect genuine evidence integration rather than surface-level artifacts. We evaluate 12 open-weight vision-language models (VLMs) on binary classification across two clinical neuroimaging cohorts, \textsc{FOR2107} (affecti...
RESULT
ScienceToStartup currently rates this 4.0/10 on the public viability pass. Our findings demonstrate that surface evaluations are inadequate indicators of multimodal reasoning, with direct implications for the deployment of VLMs in clinical settings. Code availability is flagged...
WHY NOW
Clinical VLM Evaluation moved forward this cycle; last verified April 2026. Public score 4.0/10. Production flags indicate code availability.
smaller VLMs exhibit gains of up to 58% F1 upon introduction of neuroimaging context
Explicitly stated in the abstract with a specific numeric metric (58% F1).
partial
merely mentioning MRI availability in the task prompt accounts for 70-80% of this shift, independent of whether imaging data is present
Directly stated in the abstract with a precise percentage range (70-80%).
partial
a domain-specific instance of modality collapse we term the scaffold effect
The term 'scaffold effect' is explicitly defined in the abstract as the cause of the performance shift.
partial
Expert evaluation reveals fabrication of neuroimaging-grounded justifications across all conditions
Strongly stated in the abstract, though the specific details of the 'expert evaluation' are elaborated in the analysis excerpt.
partial
preference alignment, while eliminating MRI-referencing behavior, collapses both conditions toward random baseline
Directly stated in the abstract as a key finding.
partial
Prior work on this cohort using classical ML pipelines found classification accuracies of only 54–56% with univariate neuroimaging markers
Explicitly stated in the methodology section with a citation to prior work and specific accuracy figures.
partial
with distilled models becoming competitive with counterparts an order of magnitude larger
Directly stated in the abstract, though the mechanism (the scaffold effect) is implied as the enabling condition.
partial
Our findings demonstrate that surface evaluations are inadequate indicators of multimodal reasoning
This is the central conclusion of the paper, explicitly stated in the abstract.
partial
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This research reveals a critical 'scaffold effect' in clinical vision-language models, where prompt framing, not actual data integration, drives apparent performance gains, highlighting a significant risk for clinical deployment.
Segment
Clinical VLM Evaluation
Adoption evidence
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reason
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proof status
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confidence low
next verification path
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Evidence coverage
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37 refs / 3 sources / 50% coverage
stale
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Evidence
37 references, 3 sources, 50% evidence coverage.
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Write integration checklist from prototype path and target workflow.
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