ScienceToStartup is an Agent Operating System for Research Commercialization

As Large Language Models (LLMs) advance toward embodied AI agents operating in physical environments, a fundamental question emerges: can models trained on text corpora reliably reason about complex physics while adhering to safety constraints? We address this through PilotBench, a benchmark evaluating LLMs on safety-critical flight trajectory and attitude prediction. Built from 708 real-world general aviation trajectories spanning nine operationally distinct flight phases with synchronized 34-channel telemetry, PilotBench systematically probes the intersection of semantic understanding and physics-governed prediction through comparative analysis of LLMs and traditional forecasters. We introduce Pilot-Score, a composite metric balancing 60% regression accuracy with 40% instruction adherence and safety compliance. Comparative evaluation across 41 models uncovers a Precision-Controllability Dichotomy: traditional forecasters achieve superior MAE of 7.01 but lack semantic reasoning capabilities, while LLMs gain controllability with 86--89% instruction-following at the cost of 11--14 MAE precision. Phase-stratified analysis further exposes a Dynamic Complexity Gap-LLM performance degrades sharply in high-workload phases such as Climb and Approach, suggesting brittle implicit physics models. These empirical discoveries motivate hybrid architectures combining LLMs' symbolic reasoning with specialized forecasters' numerical precision. PilotBench provides a rigorous foundation for advancing embodied AI in safety-constrained domains.

AI-based weather forecasting now rivals traditional physics-based ensembles, but state-of-the-art (SOTA) models rely on specialized architectures and massive computational budgets, creating a high barrier to entry. We demonstrate that such complexity is unnecessary for frontier performance. We introduce U-Cast, a probabilistic forecaster built on a standard U-Net backbone trained with a simple recipe: deterministic pre-training on Mean Absolute Error followed by short probabilistic fine-tuning on the Continuous Ranked Probability Score (CRPS) using Monte Carlo Dropout for stochasticity. As a result, our model matches or exceeds the probabilistic skill of GenCast and IFS ENS at 1.5$^\circ\$ resolution while reducing training compute by over 10$\times$ compared to leading CRPS-based models and inference latency by over 10$\times$ compared to diffusion-based models. U-Cast trains in under 12 H200 GPU-days and generates a 60-step ensemble forecast in 11 seconds. These results suggest that scalable, general-purpose architectures paired with efficient training curricula can match complex domain-specific designs at a fraction of the cost, opening the training of frontier probabilistic weather models to the broader community. Our code is available at: https://github.com/Rose-STL-Lab/u-cast.

While Large Language Models (LLMs) have demonstrated significant potential in Tool-Integrated Reasoning (TIR), existing training paradigms face significant limitations: Zero-RL suffers from inefficient exploration and mode degradation due to a lack of prior guidance, while SFT-then-RL is limited by high data costs and capability plateaus caused by low-entropy collapse. To address these challenges, we propose E3-TIR (Enhanced Experience Exploitation), a warm-up paradigm for the early stages of agent training. Specifically, we formulate training as the dynamic integration of three experience types: Expert Prefixes, Expert Guided, and Self-Exploration. By executing diverse branching exploration around expert "anchors" and employing a mix policy optimization mechanism, we effectively mitigate distribution shifts and resolve optimization conflicts arising from shared prefixes. Our method dynamically adapts the model's knowledge boundaries, effectively balancing exploration diversity with training efficiency.Experimental results demonstrate that E3-TIR achieves a 6 performance improvement over traditional paradigms on tool-use tasks, while requiring less than 10 of the synthetic data. Furthermore, in terms of ROI, a comprehensive metric integrating performance, data cost, and training efficiency we achieve a 1.46x gain compared to baselines. Code is available at https://github.com/yuki-younai/E3-TIR.

Human action recognition is pivotal in computer vision, with applications ranging from surveillance to human-robot interaction. Despite the effectiveness of supervised skeleton-based methods, their reliance on exhaustive annotation limits generalization to novel actions. Zero-Shot Skeleton Action Recognition (ZSAR) emerges as a promising paradigm, yet it faces challenges due to the spectral bias of diffusion models, which oversmooth high-frequency dynamics. Here, we propose Frequency-Aware Diffusion for Skeleton-Text Matching (FDSM), integrating a Semantic-Guided Spectral Residual Module, a Timestep-Adaptive Spectral Loss, and Curriculum-based Semantic Abstraction to address these challenges. Our approach effectively recovers fine-grained motion details, achieving state-of-the-art performance on NTU RGB+D, PKU-MMD, and Kinetics-skeleton datasets. Code has been made available at https://github.com/yuzhi535/FDSM. Project homepage: https://yuzhi535.github.io/FDSM.github.io/

Vision-Language-Action (VLA) models have recently achieved notable progress in end-to-end autonomous driving by integrating perception, reasoning, and control within a unified multimodal framework. However, they often lack explicit modeling of temporal dynamics and global world consistency, which limits their foresight and safety. In contrast, world models can simulate plausible future scenes but generally struggle to reason about or evaluate the imagined future they generate. In this work, we present VLA-World, a simple yet effective VLA world model that unifies predictive imagination with reflective reasoning to improve driving foresight. VLA-World first uses an action-derived feasible trajectory to guide the generation of the next-frame image, capturing rich spatial and temporal cues that describe how the surrounding environment evolves. The model then reasons over this self-generated future imagined frame to refine the predicted trajectory, achieving higher performance and better interpretability. To support this pipeline, we curate nuScenes-GR-20K, a generative reasoning dataset derived from nuScenes, and employ a three-stage training strategy that includes pretraining, supervised fine-tuning, and reinforcement learning. Extensive experiments demonstrate that VLA-World consistently surpasses state-of-the-art VLA and world-model baselines on both planning and future-generation benchmarks. Project page: https://vlaworld.github.io

Large language model agents receive instructions from many sources-system messages, user prompts, tool outputs, and more-each carrying different levels of trust and authority. When these instructions conflict, models must reliably follow the highest-privilege instruction to remain safe and effective. The dominant paradigm, instruction hierarchy (IH), assumes a fixed, small set of privilege levels (typically fewer than five) defined by rigid role labels (e.g., system > user). This is inadequate for real-world agentic settings, where conflicts can arise across far more sources and contexts. In this work, we propose Many-Tier Instruction Hierarchy (ManyIH), a paradigm for resolving instruction conflicts among instructions with arbitrarily many privilege levels. We introduce ManyIH-Bench, the first benchmark for ManyIH. ManyIH-Bench requires models to navigate up to 12 levels of conflicting instructions with varying privileges, comprising 853 agentic tasks (427 coding and 426 instruction-following). ManyIH-Bench composes constraints developed by LLMs and verified by humans to create realistic and difficult test cases spanning 46 real-world agents. Our experiments show that even the current frontier models perform poorly (~40% accuracy) when instruction conflict scales. This work underscores the urgent need for methods that explicitly target fine-grained, scalable instruction conflict resolution in agentic settings.

Large Language Models (LLMs) for code generation can replicate insecure patterns from their training data. To mitigate this, a common strategy for security hardening is to fine-tune models using supervision derived from the final transformer layer. However, this design may suffer from a final-layer bottleneck: vulnerability-discriminative cues can be distributed across layers and become less detectable near the output representations optimized for next-token prediction. To diagnose this issue, we perform layer-wise linear probing. We observe that vulnerability-related signals are most detectable in a band of intermediate-to-upper layers yet attenuate toward the final layers. Motivated by this observation, we introduce DeepGuard, a framework that leverages distributed security-relevant cues by aggregating representations from multiple upper layers via an attention-based module. The aggregated signal powers a dedicated security analyzer within a multi-objective training objective that balances security enhancement and functional correctness, and further supports a lightweight inference-time steering strategy. Extensive experiments across five code LLMs demonstrate that DeepGuard improves the secure-and-correct generation rate by an average of 11.9% over strong baselines such as SVEN. It also preserves functional correctness while exhibiting generalization to held-out vulnerability types. Our code is public at https://github.com/unknownhl/DeepGuard.

The rapid proliferation of Large Language Model (LLM) providers--each exposing proprietary API formats--has created a fragmented ecosystem where applications become tightly coupled to individual vendors. Switching or bridging providers requires $O(N^2)$ bilateral adapters, impeding portability and multi-provider architectures. We observe that despite substantial syntactic divergence, the major LLM APIs share a common semantic core: the practical challenge is the combinatorial surface of syntactic variations, not deep semantic incompatibility. Based on this finding, we present LLM-Rosetta, an open-source translation framework built on a hub-and-spoke Intermediate Representation (IR) that captures the shared semantic core--messages, content parts, tool calls, reasoning traces, and generation controls--in a 9-type content model and 10-type stream event schema. A modular Ops-composition converter architecture enables each API standard to be added independently. LLM-Rosetta supports bidirectional conversion (provider-to-IR-to-provider) for both request and response payloads, including chunk-level streaming with stateful context management. We implement converters for four API standards (OpenAI Chat Completions, OpenAI Responses, Anthropic Messages, and Google GenAI), covering the vast majority of commercial providers. Empirical evaluation demonstrates lossless round-trip fidelity, correct streaming behavior, and sub-100 microsecond conversion overhead--competitive with LiteLLM's single-pass approach while providing bidirectionality and provider neutrality. LLM-Rosetta passes the Open Responses compliance suite and is deployed in production at Argonne National Laboratory. Code is available at https://github.com/Oaklight/llm-rosetta.

AI coding tools are widely adopted, but most teams plateau at prompt-and-review without a framework for systematic progression. This paper presents the AI Codebase Maturity Model (ACMM), a 5-level framework describing how codebases evolve from basic AI-assisted coding to self-sustaining systems. Inspired by CMMI, each level is defined by its feedback loop topology the specific mechanisms that must exist before the next level becomes possible. I validate the model through a 4-month experience report maintaining KubeStellar Console, a CNCF Kubernetes dashboard built from scratch with Claude Code (Opus) and GitHub Copilot. The system currently operates with 63 CI/CD workflows, 32 nightly test suites, 91% code coverage, and achieves bug-to-fix times under 30 minutes 24 hours a day. The central finding: the intelligence of an AI-driven development system resides not in the AI model itself, but in the infrastructure of instructions, tests, metrics, and feedback loops that surround it. You cannot skip levels, and at each level, the thing that unlocks the next one is another feedback mechanism. Testing the volume of test cases, the coverage thresholds, and the reliability of test execution proved to be the single most important investment in the entire journey.

While Multi-Agent Systems (MAS) are increasingly deployed for complex workflows, their emergent properties-particularly the accumulation of bias-remain poorly understood. Because real-world MAS are too complex to analyze entirely, evaluating their ethical robustness requires first isolating their foundational mechanics. In this work, we conduct a baseline empirical study investigating how basic MAS topologies and feedback loops influence prejudice. Contrary to the assumption that multi-agent collaboration naturally dilutes bias, we hypothesize that structured workflows act as echo chambers, amplifying minor stochastic biases into systemic polarization. To evaluate this, we introduce Discrim-Eval-Open, an open-ended benchmark that bypasses individual model neutrality through forced comparative judgments across demographic groups. Analyzing bias cascades across various structures reveals that architectural sophistication frequently exacerbates bias rather than mitigating it. We observe systemic amplification even when isolated agents operate neutrally, and identify a 'Trigger Vulnerability' where injecting purely objective context drastically accelerates polarization. By stripping away advanced swarm complexity to study foundational dynamics, we establish a crucial baseline: structural complexity does not guarantee ethical robustness. Our code is available at https://github.com/weizhihao1/MAS-Bias.