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ARXIV:2604.08502 · MEDICAL AI · SUBMITTED 10 APR · 17:40 UTC · FRESHNESS STALE
ARXIV:2604.08502MEDICAL AISUBMITTED 10 APR · 17:40 UTCFRESHNESS STALEKabilan Elangovan · Daniel Ting · arXiv
The C-Score metric quantifies explanation consistency in medical image classification, providing an early warning signal of model instability and enabling architecture-specific deployment recommendations.
Opportunity summary
Pain The C-Score metric quantifies explanation consistency in medical image classification, providing an early warning signal of model instability and enabling architecture-specific deployment recommendations.
Evidence 0 refs | 3 sources | 50% coverage
Blocker Evidence unverified
The C-Score metric quantifies explanation consistency in medical image classification, providing an early warning signal of model instability and enabling architecture-specific deployment recommendations. However, existing evaluation frameworks assess whether explanations are correct, measured by…
Class Activation Mapping (CAM) methods are widely used to generate visual explanations for deep learning classifiers in medical imaging. However, existing evaluation frameworks assess whether explanations are correct, measured by localisation fidelity against radiologist…
ScienceToStartup currently rates this 6.0/10 on the public viability pass. ScoreCAM deterioration on ResNet50V2 is detectable one full checkpoint before catastrophic AUC collapse and yields architecture-specific clinical deployment recommendations grounded in explanation quality rather…
Medical AI moved forward this cycle; last verified April 2026. Public score 6.0/10. Production flags indicate code availability.
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Score6.0Public score shown from the verified overall while the stale axis breakdown refreshesAnalysis summary
The C-Score metric quantifies explanation consistency in medical image classification, providing an early warning signal of model instability and enabling architecture-specific deployment recommendations.
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10.48550/arXiv.2604.08502The C-Score metric quantifies explanation consistency in medical image classification, providing an early warning signal of model instability and enabling architecture-specific deployment recommendations.
Abstract
Class Activation Mapping (CAM) methods are widely used to generate visual explanations for deep learning classifiers in medical imaging. However, existing evaluation frameworks assess whether explanations are correct, measured by localisation fidelity against radiologist annotations, rather than whether they are consistent: whether the model applies the same spatial reasoning strategy across different patients with the same pathology. We propose the C-Score (Consistency Score), a confidence-weighted, annotation-free metric that quantifies intra-class explanation reproducibility via intensity-emphasised pairwise soft IoU across correctly classified instances. We evaluate six CAM techniques: GradCAM, GradCAM++, LayerCAM, EigenCAM, ScoreCAM, and MS GradCAM++ across three CNN architectures (DenseNet201, InceptionV3, ResNet50V2) over thirty training epochs on the Kermany chest X-ray dataset, covering transfer learning and fine-tuning phases. We identify three distinct mechanisms of AUC-consistency dissociation, invisible to standard classification metrics: threshold-mediated gold list collapse, technique-specific attribution collapse at peak AUC, and class-level consistency masking in global aggregation. C-Score provides an early warning signal of impending model instability. ScoreCAM deterioration on ResNet50V2 is detectable one full checkpoint before catastrophic AUC collapse and yields architecture-specific clinical deployment recommendations grounded in explanation quality rather than predictive ranking alone.
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PROBLEM
The C-Score metric quantifies explanation consistency in medical image classification, providing an early warning signal of model instability and enabling architecture-specific deployment recommendations. However, existing evaluation frameworks assess whether explanations are co...
METHOD
Class Activation Mapping (CAM) methods are widely used to generate visual explanations for deep learning classifiers in medical imaging. However, existing evaluation frameworks assess whether explanations are correct, measured by localisation fidelity against radiologist annotat...
RESULT
ScienceToStartup currently rates this 6.0/10 on the public viability pass. ScoreCAM deterioration on ResNet50V2 is detectable one full checkpoint before catastrophic AUC collapse and yields architecture-specific clinical deployment recommendations grounded in explanation quality...
WHY NOW
Medical AI moved forward this cycle; last verified April 2026. Public score 6.0/10. Production flags indicate code availability.
Abstract-backed public claims while anchored extraction refreshes.
The C-Score metric quantifies explanation consistency in medical image classification, providing an early warning signal of model instability and enabling architecture-specific deployment recommendations. However, existing evaluation frameworks assess whether explanations are correct, measured by localisation fidelity against radiologist annotations, rather than whether they are consistent: whether the model applies the same spatial reasoning strategy across different patients with the same pathology.
Abstract-backed fallback claim; anchored extraction has not materialized a public claim row yet.
partial
Class Activation Mapping (CAM) methods are widely used to generate visual explanations for deep learning classifiers in medical imaging. However, existing evaluation frameworks assess whether explanations are correct, measured by localisation fidelity against radiologist annotations, rather than whether they are consistent: whether the model applies the same spatial reasoning strategy across different patients with the same pathology.
Abstract-backed fallback claim; anchored extraction has not materialized a public claim row yet.
partial
ScienceToStartup currently rates this 6.0/10 on the public viability pass. ScoreCAM deterioration on ResNet50V2 is detectable one full checkpoint before catastrophic AUC collapse and yields architecture-specific clinical deployment recommendations grounded in explanation quality rather than predictive ranking alone. Code availability is flagged in the production record; the public repository link still needs proof alignment.
Abstract-backed fallback claim; anchored extraction has not materialized a public claim row yet.
partial
Medical AI moved forward this cycle; last verified April 2026. Public score 6.0/10. Production flags indicate code availability.
Abstract-backed fallback claim; anchored extraction has not materialized a public claim row yet.
partial
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The C-Score metric quantifies explanation consistency in medical image classification, providing an early warning signal of model instability and enabling architecture-specific deployment recommendations.
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